Chemicals such
as phthalates, polychlorinated biphenyls (PCBs) and biphenyl A (BPA)—endocrine
disruptors that can mimic the body’s natural hormones—could be contributing to
fertility problems.
Although it’s
likely that such chemicals are involved in infertility, it’s notoriously hard
to tease out the root causes of such problems in humans, according to Russ
Hauser, Frederick Lee Hisaw Professor of Reproductive Physiology at Harvard
T.H. Chan School of Public Health.
“There’s pretty
solid evidence that exposure to lead can cause infertility, but there’s a whole
lot of other exposures for which the evidence is mixed or inconclusive,” said
Hauser in a June 23, 2014 podcast from the Partnerships for Environmental
Public Health (PEPH) program, part of the National Institute of Environmental
Health Sciences. He said that most studies have measured people’s environmental
exposures based on what they’ve been exposed to recently, but the more
important exposures may be those that occurred years earlier, either in utero
or during puberty.
More research is
needed, Hauser said. In the meantime, because the use of these potentially
harmful chemicals is widespread and they are often not listed on product
labels, “the decision to reduce the population’s exposure needs to be made at
the governmental level in terms of regulations,” he said. (This article was
first published on Harvard T.H. Chan School of Public Health)
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